자연 발기가 더 밝은 ...

An undated publicity photo of Pfizer's Viagra drug. A major AIDS advocacy and treatment group

on Friday asked drugmaker Pfizer Inc. to pull advertisements encouraging use of the impotence

pill Viagra on New Year's Eve, blasting the ads as recklessly encouraging recreational use

of the drug. REUTERS/PRNewsFoto

만가지 쾌락의 최상품으로 젊은이에서 실제 발기 불능 환자에 이르기까지

엄청난 사용이 전세계적으로 번지고 있는 비아그라와 후발 약품 씨알리스

등이 심장질환이나 고혈압의 병적이 있는 경우에는 시력에 문제를 야기하고

색갈 구별 능력까지도 저하시킨다고. 자 이제는 한 번 돌아보자구요. 긴 시간을

즐기겠다고, 더 큰 즐거움을 느끼겠다고 멀쩡한 젊은 사람들이 그랗게 많이

사용한다는 데, 남자 자신의 쾌감을 추구하는 건지 아님 상대 파트너 여인의

즐거움을 위한 것인지, 어쨌든 이젠 자연의 분기탱천하는 발기력으로 승부를 ...

Impotence Drugs Linked Again to Vision Problems

By Alan Mozes
HealthDay Reporter Wed Jan 18, 11:47 PM ET

WEDNESDAY, Jan. 18 (HealthDay News) -- Using Viagra or Cialis could increase a risk for vision loss

in men who have a history of heart attacks or high blood pressure, researchers report.

Experts have long noted temporary light sensitivity and color vision problems as possible side effects

of the two erectile dysfunction drugs, which are taken by an estimated 23 million American men and already

carry a vision warning on their labels.

However, this is the first study to highlight serious optic nerve damage, clinically known as nonarteritic anterior

ischaemic optic neuropathy, or NAION, as a potential side effect.

"For the man who's in good health, our results don't suggest that there's a problem," said study lead author

Gerald McGwin, Jr., an associate professor with the department of epidemiology and ophthalmology in the School

of Medicine at the University of Alabama at Birmingham.

"But, clearly, there is a relationship between the use of Viagra and this eye condition, and the increased risk

seems to be limited to men who have a history of either hypertension or heart attack," he added.

NAION is estimated to strike up to 6,000 Americans over the age of 40 each year.

One quarter of patients who develop the condition in one eye will eventually develop it in the other. Between

30 percent and 40 percent of patients eventually recover some of their vision loss, but for most patients eyesight

does not improve, or even gets worse.

For the current study, McGwin and his colleagues reviewed the health and habits of 78 men who sought care

at an ophthalmology clinic in Alabama between 2000 and 2004.

Half the patients, most of whom were white, were diagnosed with NAION, while the other half were treated for

a range of other eye problems.

Reporting in the current issue of the British Journal of Ophthalmology, the authors found that patients taking

Viagra and/or Cialis who also had a history of heart attack were almost 11 times more likely to develop NAION

than patients who had no similar heart history and did not take either medication.

Patients using Viagra or Cialis without any history of heart attack were at no raised risked for NAION, the

researchers added.

Viagra/Cialis patients with a history of high blood pressure were also seven times more likely to develop NAION,

the study found. The authors stress, however, that the risk for these patients was weaker, only approaching

borderline statistical significance.

And they cautioned that the strength of the observed associations -- if they hold up under future studies --

remains, as yet, unclear.

How might erectile dysfunction drugs like Viagra and Cialis boost eye risks? McGwin and his team speculate

the medications might damage the head of the optic nerve by increasing levels of a gas called nitric oxide,

normally present in the blood.

As well, they noted that heart disease, high blood pressure and diabetes are all risk factors for damage to

the optic nerve. Patients with such medical issues might be already be at high risk for NAION, and use of

anti-impotence drugs could exacerbate the problem.

The researchers concluded that, for now, patients whose medical background includes heart attacks or high

blood pressure should be informed about the possible connection to NAION when being prescribed erectile

dysfunction medications.

"This is an issue that the FDA is concerned about, and clearly we found fairly strong evidence," said McGwin.

"But I would be cautious about making clinical recommendations to any patient based on a single small study

that involved less than 100 people [and] that wasn't a clinical trial. I'm not trying to dismiss what we found.

We found a strong association. But a change in behavior? That's really up to the patient and his physician."

Dr. Howard D. Pomeranz, from the ophthalmology department at North Shore Long Island Jewish Health System

in Great Neck, N.Y., was the author of an accompanying editorial on the study and concurred with McGwin that

there should be no rush to judgment on the issue.

"People who are concerned about whether they might be at risk should discuss it with their physician or

ophthalmologist," he said. "And if anyone has had any visual issues that might be connected to the drugs

they're taking they should check it out," Pomeranz said.

"But, realistically, the number of people who are going to be affected by this is going to be very small,"

he stressed. "This should not be a cause for widespread alarm for people using these drugs. There have only

been several dozen vision cases among the millions who use these drugs."

The current finding comes on the heels of a case report of seven patients released in March 2005 by the University of Minnesota Medical School. That report also found potential links between erectile dysfunction drug use and NAION.

In July 2005 the U.S. Food and Drug Administration decided to alter the labeling of Viagra (sildenafil), Cialis

(tadalafil), and a third drug, Levitra (vardenafil) to warn of possible serious visual side effects. The labeling also

cautioned all patients who experienced sudden vision loss to cease taking the drugs and seek immediate medical

attention.

In a statement released late last May, Pfizer, the maker of Viagra, said "a review of 103 Viagra clinical trials

involving 13,000 patients found no reports of non-arteritic anterior ischemic optic neuropathy (NAION)." The company

added that, "there is no evidence showing that NAION occurred more frequently in men taking Viagra than men of

similar age and health who did not take Viagra."